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In Embodiment 2 of this disclosure are compounds of Formula I, or any one of Embodiments 1, or a pharmaceutically acceptable salt of any of the foregoing, wherein R 1 is a) phenyl substituted with one or two substituents selected from: hydroxy, halogen, CN, C 1-3 alkyl, C 1-3 alkyl-CN, OC 1-3 alkyl-CN, C 1-3 haloalkyl, C 3-6 cycloalkyl, OC 1-3 alkyl, OC 1-3 haloalkyl, O-cyclopropyl, 5 membered heteroaryl containing 2 nitrogen atoms, S(O) 2 C 1-3 alkyl, S(O) 2 NHC 1-3 alkyl, or C 1-3 alkylNH 2 , and wherein the alkyl moiety is optionally further substituted with cyano, and wherein the cycloalkyl moiety is optionally further substituted with F, CH 3 , CF 3 , CN, or OH

10.1007/s00406-016-0758-6 4 ChungH.KimA.LimK