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ALDH2 rs671 polymorphism may expedite the onset and progression of cardiovascular diseases by modulating biological processes such as autophagy, apoptosis, and oxidative stress in cardiomyocytes and VSMCs through ROS-mediated lipid peroxidation (99)

Hemodynamic Effects: By inducing smooth muscle contraction in the vasculature, phenylephrine significantly increases peripheral resistance, which elevates both systolic and diastolic blood pressure (SBP & DBP)

Supplementary material The Supplementary Material for this article can be found online at: References 1 AkiyamaS.FukudaS.SteinbergJ

After six weeks of weekly infusions, the flare-ups were decidedly calmer