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[PubMed] [Google Scholar] 62.Axis-Shield Clinical utilityCorrelation between Active-B12 and Total B12

You may need a supplement if you: Eat a vegetarian or vegan diet and dont consume enough foods that contain the vitamins Take heartburn medications Have had weight loss surgery Have a disease that affects your stomach lining or gut, such as IBD or Crohns disease Have or are at risk of getting age-related macular degeneration (AMD) Are older and dont get enough B vitamins through your diet In many cases, you may not need a B complex supplement, but a single B vitamin supplement

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This has made it standard in muscle cell culture, cancer cell biology, and various other in vitro settings