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HIV-1 resistance substitutions may emerge in individuals with undiagnosed HIV-1 infection who are taking only YEZTUGO, because YEZTUGO alone does not constitute a complete regimen for HIV-1 treatment [see Warnings and Precautions (5.2)]

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A recent study showed that pharmaceutical inhibition of MEK1/2 promotes fatty acid oxidation and confers a stem cell-like memory phenotype to CD8 + T cells [65]

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Mullan BA, Young IS, Fee H, McCance DR

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