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Designing nanozymes for in vivo applications

Cells were incubated another 24 h before treatment, harvesting and analysis

Alterations in oxygen consumption, respiratory quotient, and heat production in long-lived GHRKO and Ames dwarf mice, and short-lived bGH transgenic mice

In this contest, ZnT8 deficiency combined with a high-fat diet significantly exacerbated the effects caused by the absence of this zinc store alone and contributes to increased obesity (283) ( Figure 3E a, c)