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As no tumor can grow without anabolic substrates or energy, the simultaneous targeting of glycolysis and glutaminolysis is expected to reduce the proliferation of most if not all GBM cells

The involvement of peptide donor groups (S-thiol and N-imidazole) and non-protein ligands (as sulfide anions) in metal chelation, as well as secondary structure elements, was demonstrated

[DOI] [PubMed] [Google Scholar] 21.Linazi G., Abudureyimu S., Zhang J., Wulamu A., Maimaitiaili M., Wang B., Bakeer B., Xi Y

Although sperm cryopreservation prior to gonadotoxic therapy is a standard fertility-preserving approach [21], freezing and thawing processes often result in cryoinjury, reducing sperm viability, membrane integrity, and motility [22, 23]