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To address the ROS burst driven by ferroptosis and the imbalance of iron homeostasis, a study has developed a macrophage-targeting polysaccharide iron nanoenzyme, which possesses dual enzyme activities resembling catalase and peroxidase, capable of scavenging ROS, inhibiting lipid peroxidation, and controllably releasing Fe 2 to correct systemic iron deficiency [150]

Updated July 2026

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