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On the other hand, UVB-induced tyrosine nitration in melanocytes stimulates main photosensitizers, including methylene blue and pheomelanin, to reversely enhance ROS generation 99

Advancements in genetic techniques have led to substantial progress in developing conventional lines with improved oxidative stress tolerance or by developing transgenic lines with modified antioxidant levels

However, it is vital to remember that no single supplement is a miracle cure for complex chronic illness

Therefore, this section focuses on the pathological damage, molecular mechanisms, and prognostic impact of Cu dysregulation in DM and its complications ( Table 2 ) ( Figure 2 )