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Hydration, proper dosing, nutrition, and provider monitoring may help reduce unwanted effects

Clinical implication Clinicians are encouraged to perform comprehensive evaluations prior to prescribing GLP-1 RA therapy in patients with a history of pancreatic disorders or other pancreatitis risk factors

The C57BL/6 depilation model, the most commonly used mouse model in the field, measures hair regrowth after forced removal of all body hair, which creates a synchronized, uniform anagen response that does not accurately replicate the patchy, progressive follicle miniaturization of androgenetic alopecia or the diffuse shedding of telogen effluvium

They are calibrated in insulin units rather than standard volume units (e.g