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Acknowledgments We would like to thank all the researchers involved in this study

Nf-kappab-dependent and -independent epigenetic modulation using the novel anti-cancer agent dmapt

Several recent studies employing this methodology have uncovered that traditional memory-enhancing formulas regulate PI3K/AKT, Nrf2, MAPK, and NF-B pathways key nodes in the AD signaling network ( 2.5.1 Multi-omics approaches and systems biology in Alzheimers research Recent advances in multi-omics technologiesincluding transcriptomics, metabolomics, proteomics, and spatial transcriptomicshave opened new avenues for elucidating the molecular mechanisms through which natural products influence AD pathogenesis (Ma et al., 2024a)

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