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(PubMed) Wu K, Helzlsouer KJ, Comstock GW, Hoffman SC, Nadeau MR, Selhub J

Therefore, the severe interstitial edema, more expressed in white than in gray mater, and severe neuron loss in hippocampal neurons, neurons of dentate nucleus, Purkinje cells and other cerebellar nuclei and less severe damage in the pons, the mesencephalon and lateral geniculate body could be a specific paracetamol effect and these territories could be involved in the occurrence of maximal paracetamol induced seizures

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Some patients self-inject after adequate training in aseptic technique and safe sharps disposal, but others prefer clinician administration at office visits