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doi: 10.1007/978-1-4615-1833-4_1 38 YoshidaK.HirokawaJ.TagamiS.KawakamiY.UrataY.KondoT

They found that microbial infections, such as SARS and H5N1 virus infections in the lungs, trigger NADPH-dependent ROS production, thereby generating oxidized phospholipids, such as oxidized 1-palmitoyl-2-arachidonoyl-sn-glycerol-3-phosphatidylcholine, to induce lung injury and cytokine production by lung macrophages via TLR4TRIF 80