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The term "hypolipidemic agents", as used herein, refer to substances other than PPAR agonist and fibrates that lower the lipid low density lipoproteins (LDL) and/or increase the high density lipoprotein (HDL) in blood

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This minimally invasive method allows the therapeutic ingredients to reach directly into the deeper layers of the skin, where melanin production takes place and thus ensures the best possible absorption and effectiveness

It was also reported that microglia are capable of removing incorrectly deposited myelin directly from the axon, contributing to the refinement of myelin sheaths, as shown in zebrafish and mice during development (Hughes and Appel, 2020