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These same studies also found improvements in mitochondrial function, metabolic markers, and reductions in oxidative stress and inflammation

Retatrutides Phase 2 monotherapy weight loss (~24.2% at 48 weeks) is numerically larger than cagrilintides (~10.8% at 26 weeks), but those come from different trials, durations, and doses, and cagrilintides strongest data are as the CagriSema combination

It is important to maintain adequate B12 levels, especially in patients with thyroid disorders

Pernicious anemia is associated with an increased incidence of carcinoma of the stomach, but this is believed to be related to the underlying pathology and not to treatment with vitamin B 12