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The magnitude of difference was particularly notable for weight loss, suggesting that GIP receptor activation contributes meaningfully to metabolic improvements beyond GLP-1 effects alone

In the cumulative toxicity test, Kunming mice were injected with 500 mg kg 1 LAAM GSH-CQDs on days 0, 4, and 7, respectively, and the dose was increased to 1000 mg kg 1 on days 10 and 13, with an accumulated dose of 3500 mg kg 1