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In humans, metabolically healthy obesity is associated with smaller adipocytes and a lower visceral-to-subcutaneous fat ratio, whereas expansion of visceral fat correlates with systemic insulin resistance and ectopic lipid deposition 46,47,48

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doi: 10.1016/j.ajog.2016.01.182 223 Chamorro-GarciaRSahuMAbbeyRJLaudeJPhamNBlumbergB

The goal is to maximize its regenerative and reparative benefits while minimizing any temporary adverse observations