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10.3389/fphar.2018.01181 130 ZhouQ.WuX.LiuY.WangX.LingX.GeH.et al (2020)

Abbreviations ACR American College of Rheumatology CLE cutaneous lupus erythematosus DLE discoid lupus erythematosus ICAM intracellular adhesion molecule IFN interferon IL interleukin LET lupus erythematosus tumidus SLEDAI systemic lupus erythematosus disease activity index MED minimal erythema dose MTD minimal tanning dose PMLE polymorphous light eruption SLAM systemic lupus activity measure SLE systemic lupus erythematosus TNF tumor necrosis factor UVA ultraviolet-A UVB ultraviolet-B UVR ultraviolet radiation Footnotes Conflict of Interest: Benjamin Chong is an investigator for Amgen Incorporated, Celgene Corporation, and Daavlin Corporation

The blots were washed and then incubated with a secondary antibody conjugated to horseradish peroxidase (Jackson ImmunoResearch Laboratories, West Grove, PA, USA), and the blots were visualized using a western blotting luminol reagent kit (Santa Cruz Biotechnology, Santa Cruz, CA.)

In the early phase, within the first week of treatment, oligodendrocyte death can be observed as early as two days after treatment begins