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GSTs may participate in the detoxification of microbial toxins or in antioxidative reactions

Given the smaller sample size of children with Stage 2, we next combined the most severe stages (2 and 3) and assessed differences in GPx3 concentration, to increase statistical confidence

Whilst the location of the substrate supply defect differed between the studies both suggest TCA cycle disturbance in ME/CFS driven by a reduced supply of glucose-derived substrate