Hepcidin is negatively regulated by TMPRSS6, which inhibits hepcidin expression by suppressing Hjv activity and the bone morphogenetic protein-signaling pathway
You're a strong candidate for B12 injections if you experience any of the following: Persistent fatigue that sleep doesn't fix Brain fog, forgetfulness, or trouble concentrating Low mood, anxiety, or stress that feels disproportionate to what's happening Weight gain or difficulty losing weight despite consistent effort Tingling, numbness, or weakness in hands or feet (signs of B12-related neuropathy) Frequent colds, slow healing, or post-COVID fatigue A plant-based, vegetarian, or vegan diet Age 50 or older (B12 absorption naturally declines with age) A history of gastric bypass, Crohn's disease, celiac disease, or chronic acid reflux Long-term use of metformin (for diabetes), proton pump inhibitors (Prilosec, Nexium), or H2 blockers (Pepcid, Zantac) An MTHFR gene variant or known methylation issue A history of B12 deficiency, pernicious anemia, or low folate Hormonal shifts: perimenopause, menopause, postpartum If you fit one or more of these, a vitamin B12 shot is one of the lowest-risk, fastest-acting interventions available
BENEFITS OF VITAMIN B12 Injections Also known as the energy vitamin Can help with memory, heart, nervous system, and mobility Can help boost energy and metabolism Also known as the sunshine vitamin Can help with bone health, heart health, and the immune system Can help reduce depression, joint pain, and migraines Can help maintain a healthy weight and reduce the risk of diabetes Vitamin injections can help correct nutritional deficiencies Vitamin injections can help relieve health symptoms Vitamin injections can help increase energy and combat fatigue Vitamin injections can help remove environmental toxins from the body SIGNS of VITAMIN B12 DEFICIENCY Fatigue, weakness Nerve damage with numbness, tingling in the hands and legs Memory loss, confusion Dementia Depression Seizures Megaloblastic anemia Pernicious anemia
In 2016 the FDA strengthened these warnings and emphasised the association of FQs with disabling and potentially permanent serious side effects, the risks of which generally outweigh the benefits in treatments for acute bacterial sinusitis, chronic bronchitis and uncomplicated urinary tract infections
