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To determine whether induced expression of IRF5 and IKK effectively reprogrammed macrophages from M2 to M1, researchers generated M2 macrophages by culturing bone marrow-derived macrophages (BMDMs) with IL-4

It was originally developed by researchers studying mitochondrial dysfunction in degenerative diseases and has since become one of the most studied mitochondria-targeted compounds in medicine

Key Points for Patients It is a chronic condition: Crohns disease cannot currently be cured, but it can be managed effectively with the right treatment

Noah John Hoffschneider, junior, Deans List, College of Engineering, mechanical engineering