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(2.1, 4.2, or 8.4 g/kg) for six weeks alleviated hepatic steatosis, oxidative stress, and inflammation in ALD rats via the gutliver axis by modulating the overall structure of the GM, such as maintaining the Firmicutes/Bacteroidetes ratio and reducing the relative abundance of harmful bacteria including Clostridium and Faecalibaculum, while activating the 15d-prostaglandin J2/Peroxisome proliferator-activated receptor (PPAR) and PPAR signaling pathways to lower serum levels of TNF-, IL-1, and IL-6, thereby improving lipid metabolism [121]

Even the lowest dose outperformed existing alternatives

Despite its benefits, challenges persist, including optimizing selenium dosage to prevent toxicity, addressing variability in selenium uptake among species, and minimizing environmental impacts such as soil contamination

Just 12 nuts a day is usually enough