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[11] Levine LA, Burnett AL

Arshi, A., Nakashima, Y., Nakano, H., Eaimkhong, S

Timing matters in CIPN

It works through two mechanisms: inhibiting the enzyme tyrosinase (which is essential for melanin synthesis) and shifting the melanin production pathway from eumelanin (darker pigment) to pheomelanin (lighter pigment)