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focal melanotic macule

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Oral pathology: Noting a pigmented macule that often presents a diagnostic dilemma Registered Dental Hygienists Is focal melanotic lesion potentially malignant? A case report ScienceDirect Differential Diagnosis of Pigmented Lesions in the Oral Mucosa: A Clinical Based Overview and Narrative Review PMC Melanotic Macules, Naevi, and Melanoma Springer Nature Link

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They may represent slow and insidious systemic dysfunction and/or collapse which evolves over long time periods

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Moreover, SZD treatment reduced the expression level of HIF-1 and its subsequent transcriptional target VEGF, which in turn reduced the angiogenesis and decreased the volume of endometriotic lesions

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