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Dave Asprey, founder of Bulletproof and a prominent biohacker, has discussed 5-Amino-1MQ in combination with other peptides, highlighting "a lot of buzz about this peptide especially in combination with the 5-amino 1MQ."[28] He suggests it for biohackers seeking metabolic hacks without extreme diets

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People with Absorption Issues Several conditions can impair B12 absorption: Pernicious anaemia An autoimmune condition thats the most common cause of severe B12 deficiency in the UK Crohns disease or coeliac disease Previous gastric surgery Including gastric bypass Chronic use of certain medications Including proton pump inhibitors (PPIs), metformin, and some anti-seizure medications Others at Risk Pregnant and breastfeeding women (who have increased B12 requirements) Heavy alcohol consumers Those with chronic inflammation affecting gut health People taking certain oral contraceptives B12 Deficiency in the UK: How Common Is It