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How long does it take to start feeling refreshed after a Vitamin B12 shot

M., & Burris, T

[1] [4] Mood changes including low mood, irritability, or anxiety can be associated with declining B12 levels, though these symptoms are non-specific and can have many causes

The four forms (vitamins) of B12 are all deeply red colored crystals and water solutions, due to the color of the cobalt-corrin complex (biologically relevant enzyme, it is the "core" of vitamin B12)