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For example, a bile acid metabolite (gut microbiome-derived glycochenodeoxycholic acid) activates the TFR/ACSL4 pathway to induce ferroptosis, promoting progression of environmental toxin-associated metabolic dysfunction-associated fatty liver disease (Liu et al., 2022a)

Small actionslike staying hydrated, breathing clean air, and taking moments to restcan make a big difference

65,75,217,218 Moreover, previous studies have shown that NETs promote cancer metastasis by trapping circulating tumor cells

Gene expression profiling revealed pro-inflammatory responses in the liver of FBXL5 CD11c mice To investigate the mechanisms underlying the exacerbation of liver inflammation in APAP-treated FBXL5 CD11c mice, we performed RNA sequencing of whole liver of the control and FBXL5 CD11c mice with or without APAP treatment for 6 h