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Schedule is 5 days on, 2 days off: every month, across a 3-month active cycle, followed by a 2-month rest before repeating

Enhancing GSH, mainly through NAC, GSH precursors or pro-GSH compound administration, becomes a potential treatment option for SARS-CoV-2 infection and COVID-19 disease by reducing oxidative stress and cytokine expression especially in diabetic patients at risk of more severe disease (Singh et al., 2022)

Changes in chemokine and growth factor levels may be useful biomarkers for monitoring disease severity in COVID-19 patients

This paradigm has changed our way of thinking in defining predictive biomarkers for antiangiogenic therapy