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Kefirs microbial metabolism produces numerous bioactive peptides, with 257 identified peptides mainly derived from -casein, among which 16 show ACE-inhibitory, antimicrobial, immunomodulatory, antioxidant, and antithrombotic activities (Ebner et al., 2015)

Approximately 64.0 22.8% of the toxin dose is excreted renally in its unmodified form or as a glucuronic acid conjugate (Warth et al

Consequently, NRF2 SUMOylation plays a key role in promoting signaling pathways that support HCC tumorigenesis, both under normal conditions and in response to metabolic stress [131]

Furthermore, F 405 /F 488 is insensitive to other environmental factors, including potential non-specific interactions or reactions with intracellular proteins (Fig