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Causes of increased oxidative stress are triggers of hemolytic crisis and include: Fava beans Drugs: antimalarial drugs (e.g., chloroquine, primaquine), sulfa drugs (e.g., trimethoprim-sulfamethoxazole), nitrofurantoin, isoniazid, dapsone, NSAIDs, ciprofloxacin, chloramphenicol Bacterial and viral infections (most common cause): Severe enzymatic deficiency can inhibit respiratory burst activity due to reduced NADPH production in phagocytes

10.1007/s11064-020-03030-1 Neurochem Res

A total of 15 functional groups were found to be related to cellular components, 8 groups were traced with subcellular localization, eight groups were found to be engaged in molecular functions, and the other 13 groups might well be important in plant biological processes (Figure 8)