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Colson et al., 2021

Due to the mediating position of the folate cycle between the two adjacent cycles, a folic acid deficiency has widespread consequences: the production of SAM falls, as does that of BH4 and the associated neurotransmitters

[DOI] [PubMed] [Google Scholar] 1134.Shah B., Newman J.D., Woolf K., Ganguzza L., Guo Y., Allen N., Zhong J., Fisher E.A., Slater J

Discovery of Small Molecule Acting as Multitarget Inhibitor of Colorectal Cancer by Simultaneous Blocking of the Key COX-2, 5-LOX and PIM-1 Kinase Enzymes