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Subject to sediment, shake well before use

doi: 10.1016/j.yexcr.2019.05.032 163 XueJ.ZhouD.PoulsenO.ImamuraT.HsiaoY

Abstract To develop an LCMS/MS method for simultaneous quantification of mildronate and L-carnitine, and to investigate the pharmacokinetic profile of mildronate in rats, its effect on L-carnitine homeostasis, as well as the exposure characteristics, underlying mechanisms, and their associations with therapeutic efficacy and toxicity risks