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Ferroptosis and chemotherapy The clinical utility of TMZ in glioblastoma treatment is significantly constrained by MGMT-mediated DNA repair mechanisms

[DOI] [PubMed] [Google Scholar] Huang, S.F

Glutathione has been shown to help address and reduce the risk of cataracts, glaucoma, premature aging, alcoholism, cancer, heart and liver disease, lung disorders, Alzheimers disease, Parkinsons disease, osteoarthritis, and conditions that compromise the immune system

To this end, we designed a delivery system in which promelittin is cleaved only in FAP-expressing (i.e., fibrotic) regions of the liver, resulting in melittin release into the fibrotic liver microenvironment