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Histone lactylation inhibits RAR expression in macrophages to promote colorectal tumorigenesis through activation of TRAF6-IL-6-STAT3 signaling

while it may sequester harmful substances, it can simultaneously increase cellular stress and enhance neuronal toxicity, creating a detrimental cycle

Science 299 (5603), 76

Researchers are exploring how synthetic peptides could refine orexin modulation, potentially offering more tailored solutions for sleep disorders that involve hyperarousal or disrupted circadian rhythms