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doi: 10.3389/fimmu.2025.1686175 Summary Keywords COPD, ferroptosis, immune-metabolic crosstalk, lipid peroxidation, mitochondrial dynamics, precision inhalation therapy Citation Ni F-X, Chen H-H, Jiang Z-B and Huang D-H (2026) Ironing out COPD: ferroptosis-driven immune dysregulation, metabolic rewiring, and precision therapeutic opportunities

Previous studies have demonstrated that Nrf2 plays a crucial role in responding to antioxidative stress and maintaining redox homeostasis

Calorie restriction extends yeast life span by lowering the level of NADH

In ME/CFS, a self-perpetuating cycle exists between oxidative stress and mitochondrial dysfunction