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In contrast to the growing interest in HBV from drug developers, the National Institutes of Health (NIH) spent a mere $44 million on HBV this year-and little of that went to "discovery research," Block says

It enhances both synthesis and breakdown of extracellular matrix components, such as collagen, glycosaminoglycans (including dermatan and chondroitin sulfate), and decorin, and regulates metalloproteinases and their inhibitors (Pickart, Vasquez-Soltero, and Margolina 2015)

Legal only for veterinary use , primarily to promote muscle growth in livestock Illegal for human use without a prescription Severe penalties for possession, trafficking, or distribution Trenbolone acetate is used in veterinary applications but is illegal for non-medical human use in the U.S. Drug Enforcement Administration (DEA) The underground market for Trenbolone poses serious health risks due to contamination, improper dosing, and legal consequences

Therefore, the main mechanisms and potential implication of therapies under investigation have shifted to the early brain injury, cortical spreading depolarizations, and neuro inflammation