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It showed that both genetic (CB1 / knock-out mice) and pharmacological (using a CB1 receptor antagonist-AM281) inactivation of the CB1 receptor protects against the skin fibrosis process induced by bleomycin (Marquart et al., 2010)

The main difference between hemp and other strains of cannabis such as marijuana is that there is a very low percentage of THC compound in hemp, lower than 0.3% and therefore, hemp is not normally used as a recreational drug