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TIER PLANS TIER 1 (5mg total) $269 total for 8-10 week supply Monthly cost breakdown: $107-$134 based on weekly dose Recommended if new to treatment or for those on 0.2-0.6mg/week TIER 2 (10mg total) $319 total for 8-10 week supply Monthly cost breakdown: $127-$159 based on weekly dose Recommended for those on 0.7-1.2mg/week TIER 3 (20mg total) $349 total for 8-10 week supply Monthly cost breakdown: $139-$174 based on weekly dose Recommended for those on 1.3mg/week and up MONTHLY PLANS Monthly Starter Dose $165 total for one month supply Recommended if new to treatment or for those on 0.6mg/week or less Monthly Mid Dose $180 total for one month supply Recommended for doses up to 1.25mg/week Monthly Advanced Dose $195 total for one month supply Recommended for doses of 1.3mg/week and up Empower Pharmacy - Semaglutide/B12 Injection Up to 70 days BUD

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Based on previous LC-MS/MS measurements used for establishing the LC-MS/MS response curve of CNCbl for the native SIDA method [7], a reverse LC-MS/MS response curve was obtained by plotting peak area ratios [ A ([ 15 N 13 ]-CNCbl)/ A (CNCbl)] against the molar ratios [n([ 15 N 13 ]-CNCbl)/n(CNCbl)] for the quantification of [ 15 N 13 ]-CNCbl