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Rather than manipulating hormones, suppressing appetite, or artificially stimulating the nervous system, it works at the level of basic cellular energy production and storage

Amy Yasko ( about folks with a particular mutation status for COMT & VDR Taq as best needing the below forms of B12: What is Active B12 Complete

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You may also be more likely to develop vitamin B-12 deficiency if you have: Atrophic gastritis, in which your stomach lining has thinned Pernicious anaemia, which makes it hard for your body to absorb vitamin B12 Conditions that affect your small intestine, such as Crohns disease, celiac disease, bacterial growth, or a parasite Immune system disorders, such as Graves disease or lupus Been taking certain medications that interfere with the absorption of B12