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The cost of care rises dramatically as the disease progresses, and the indirect costsparticularly those related to informal caregiving and productivity lossrepresent a significant proportion of total expenditures

Kumar S, Christophides GK, Cantera R, Charles B, Han YS, et al

In this section, we analyze four major aging-related diseasesneurodegenerative, cardiovascular, metabolic disorders, and cancerand explore how the interplay between linear time, represented by the aging process, and cyclical time, embodied by the circadian system, shapes their pathophysiology