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113 Recent interest has centered on procyanidins, polyphenolic compounds found in foods such as antioxidants with anti-inflammatory properties

Some subsets of CAFs might also produce chemokines like CCL5 or CXCL12 that can attract T cells, but once present in the CAF-rich stroma, these T cells may be trapped and exposed to suppressive signals, leading to a dominance of Tregs over effector T cells