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We note that in prior rulemaking, for example, in the CY 2013 PFS final rule, we stated, we further consider[ed] how advanced primary care practices can fit within a fee-for-service model (77 FR 68987), and in the CY 2015 PFS final rule, we stated our commitment to supporting advanced primary care, including the recognition of care management as one of the critical components of primary care that contributes to better health for individuals and reduced expenditure growth (79 FR 67715)

Rates of CLASI 50 response were significantly higher in both deucravacitinib arms (56.7% and 52.3%) compared to placebo (19.0%), and numerically greater improvements were observed as early as Week 4 and sustained through Week 52

craft IPA at 7% ABV or a large wine pour one drink can equal 1.62.1 standard drinks, making the rule even less reliable