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Jrgensen et al 368 showed that plasma levels of the LOX products LXA4 and 12-HETE could be reduced by COX-2 inhibitor etoricoxib treatment for 56 days in patients with tuberculosis

Thickening of the intima is the first structural change 92 , followed by an increase in vascular smooth muscle and the infiltration of the vessel wall by inflammatory cells, including macrophages and CD8+ T lymphocytes14