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J Investig Med 53:135142

In a clinical study, this twice daily medication demonstrated significant reductions in body weight from baseline, with average decreases totaling 6.9 to 11.7 percent

SIRT1 is also known as the "longevity gene" because of its role in reducing the risk of diabetes, obesity, metabolic syndrome, atherosclerosis and other forms of cardiovascular disease, kidney disease, liver disease, neurodegeneration, and cancer