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doi: 10.3390/nu16121955 89

The trials were too short to assess any impact on coronary heart disease or mortality

These organoselenium compounds demonstrate potent anticancer and chemopreventive properties by engaging a multitude of action mechanisms including reduction of oxidative stress, induction of apoptosis, and enhancement of chemotherapeutic drug activity (218221)

The FDA moved these peptides to Category 2 primarily due to a lack of large-scale, randomized, placebo-controlled human trials demonstrating their safety and efficacy