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227 As a result of positive research findings, a Global Consensus Position Statement on the Use of Testosterone Therapy for Women was released in 2019, which endorsed the use of testosterone in postmenopausal women with hypoactive sexual desire disorder

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Since the liver is the major site of IGF-1 production, when steatosis develops lowering insulin sensitivity, the severity of steatosis at different stages of insulin resistance and metabolic syndrome seems to be correlated with worsened circulating IGF-1 levels [234]