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In addition, cocaine activates the SrcPDGFR-NF-B pathway, which enhances CXCL10 [chemokine (C-X-C motif) ligand-1] secretion

Cordeiro S, Silva B, Martins AM, Ribeiro HM, Gonalves L, Marto J

however, robust clinical validation remains limited

Furthermore, TMAO promotes endoplasmic reticulum stress responses within podocyte cellular compartments via IRE1 and PERK pathway activation architectures, culminating in amplified production of inflammatory cytokine arsenals and accelerated apoptotic cell death trajectories (Pan et al., 2023)