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SZ95, THP-1 and HaCaT cells were seeded in a 96-well plate at a density of 1 10 5 cells/well and allowed to reach 90% confluence

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In an open-label uncontrolled clinical trial in 13 subjects with RLS, six participants had a 50% or greater reduction in symptom scores after eight weeks of treatment with dipyridamole and four participants experienced a smaller degree of improvement (Garcia-Borreguero 2018)