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Description

Acta 1801 , 9941004 (2010)

The 15 N-ammonium chloride tracing found a strong incorporation of the 15 N-ammonic nitrogen into the pyrimidine precursor molecules N -carbamoyl aspartate, dihydroorotate, and orotate at the early stage of oncogenesis in the c-MET/-catenin model and the c-MET/sgAxin1 with sgAss1 and sgArg1, which was observed at 2 to 3 weeks upon oncogene expression (Fig