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In vivo micronucleus (manually or FCM based method, standalone or integrated) In vivo Comet, option 2 Mechanism exploration & follow-up assays WuXi AppTec offers a series of additional genetic toxicology assays that complement the standard battery of GLP in vitro and in vivo assays, providing additional insights into how test articles might impact human DNA

Piasecki TM, Sher KJ, Slutske WS, Jackson KM

As you can see with the BAC calculator, it makes a drastic difference