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Bioactive peptides enhance enzymatic defence by approximately 30% and improve cognitive or metabolic indices by 1020% [187,188,189], whereas fatty acids, terpenoids, and polyamines generally yield smaller yet consistent improvements of 2030% across redox and inflammatory dimensions [28,163,190]

Humanistic and economic burden of painful diabetic peripheral neuropathy in Europe: a review of the literature

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They demonstrated that cardiac pathogenic effects were exacerbated by a Zn deficiency and alleviated by its supplementation, which suggests that Zn plays a critical role in stimulating MTs to suppress the oxidative stress-activated BCL10/CARD9/p38 MAPK pathway [80]